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Why Choose Utide Peptide Synthesis Services?

From simple linear peptides to complex modified sequences, and from crude-grade research samples to GMP-grade multi-kilogram commercial-scale productions, Utide delivers end-to-end peptide synthesis solutions tailored to diverse application scenarios.

 

We prioritize customer needs as the core of our service philosophy, with an unwavering commitment to delivering high-quality, reliable results. Our team of senior synthetic chemists who are boasting extensive expertise in peptide chemistry collaborates closely with clients to deeply understand every technical requirement, whether it involves the synthesis of simple single-sequence peptide, complex labeled products, or the reproducible preparation of large-scale screening libraries.

 

Equipped with purpose-built large-scale production facilities, our specialized technical team has the capability to handle multi-kilogram order volumes and possesses in-depth expertise in executing a broad spectrum of complex chemical reactions, ensuring the successful delivery of even the most challenging peptide projects.

 

Operating out of cutting-edge R&D laboratories and fully GMP-grade production facilities, we provide innovative technical support for early-stage drug discovery including rapid synthesis of peptide candidates for high-throughput screening, while strictly adhering to global regulatory requirements such as FDA, EMA, NMPA guidelines. Throughout the service lifecycle, we maintain exceptional customer communication and project management to ensure a seamless experience.

 

Our peptide service portfolio covers the entire value chain of peptide development: from lead compound optimization, process development, and analytical method validation/quality studies, to the stable supply of GMP-grade peptides for preclinical and clinical trials. Additionally, we excel in the rapid customization of research-grade peptides with fast turnaround times for small-batch orders and offer an extensive catalog of off-the-shelf stock peptides—empowering you to accelerate the pace of your research efficiently.

PEPTIDE SYNTHESIS METHOD

Fmoc solid-phase synthesis (standard)

GMP peptide synthesis (upon request)

QUANTITY

From 1 mg to 1 kg

PURITY

Crude to≥98%

TFAremoval upon request

LEAD TIME

Starting from 10 business days

Shipping

Ambient temperature

Peptide order

Lyophilized peptide and corresponding QC report

Standard QC report

Amino acid sequence

Purity and quantity information

Modification and conjugation information

MS and HPLC profiles (except for crude/desalted peptides)

Additional analysis (upon request)

Net peptide content analysis (N%)

Qualitative amino acid analysis (AAA)

Water content analysis

Ion chromatography analysis (TFA, HAC)

Solvent residue (DMF, ACN)

Endotoxin (<1EU/MG)

Major applications of synthetic peptides
Peptide drugs
Many peptide drugs are generated by chemical modification of natural molecules. These drugs remain invaluable for the treatment of multiple metabolic diseases.
Peptide vaccines
Vaccines are considered one of the most successful strategies of modern medicine. Conventional vaccines have relied heavily in inactive pathogens to elicit an immune response, making them hard to produce.
Peptides for tissue engineering
The discovery of cell adhesion and self-assembling peptides has opened up a new window of opportunity in tissue engineering applications.
Drug & Gene Delivery
Cell-penetrating peptides and self-assembling peptides are two increasingly important bioactive components of advanced gene and drug delivery applications .
The most widely used methods for peptide preparation
Chemical synthesis

Solid-phase synthesis

Liquid-phase synthesis

Fragment-based solid-liquid hybridization

Recombinant expression

Escherichia coli system

Yeast system

Semisynthesis
Combination of synthetic and recombinant fragments via chemical or enzymatic ligation
Useful guidelines for working with synthetic peptides
How to test the solubility of your custom synthetic peptide
The most commonly used method to test solubility is based on charge determination. For small peptides with up to 5 amino-acids, distilled water remains the first option. For other cases, you can refer to this guide:
Attribute -1 to each acidic residue (Asp / D, Glu / E) and to the terminal carboxylic acid. Then, assign +1 to each basic residues (Arg / R, Lys / K, His/h) and the terminal amine. Sum up both values to determine the overall charge of your peptide.
If the overall charge value is positive, try to dissolve your peptide in water. In case the peptide does not dissolve, acidify your solution with an acetic acid solution (10 to 30%). Add TFA if acetic acid does not allow peptide dilution du sufficient concentration.
In case the overall charge is negative and the peptide does not contain cysteine residues, try to dissolve your peptide in water. If the peptide does not dissolve, add ammonium hydroxide to obtain the desired concentration.
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